FEATURED ARTICLE
Acute vascular responses to isometric handgrip (ihg) exercise and the effects of training in persons medicated for Hypertension
Chester A. Ray and Dario I. Carrasco
The study aimed to determine whether isometric handgrip (IHG) training reduces arterial pressure and whether reductions in muscle sympathetic nerve activity (MSNA) mediate this effect. Normotensive subjects were assigned to training, sham training, or control groups. The training protocol involved four 3-minute bouts of IHG exercise at 30% of maximal voluntary contraction, four times per week for 5 weeks. Resting diastolic and mean arterial pressures significantly decreased after training, whereas systolic pressure, heart rate, and MSNA did not change. Cardiovascular responses to exercise and postexercise muscle ischemia remained unchanged. No significant changes were found in the sham or control groups. These results indicate that IHG training effectively lowers arterial pressure through mechanisms not involving changes in sympathetic nerve activity, suggesting peripheral vascular adaptations might be responsible.
Isometric handgrip training reduces arterial pressure at rest without changes in sympathetic nerve activity
Chester A. Ray and Dario I. Carrasco
The study aimed to test whether isometric handgrip (IHG) training reduces arterial pressure and if such reductions relate to changes in muscle sympathetic nerve activity (MSNA). Healthy normotensive subjects were divided into training (n=9), sham training (n=7), and control (n=8) groups. The training involved 4 sessions weekly over 5 weeks, with each session consisting of four 3-minute bouts of IHG exercise at 30% maximal voluntary contraction. Resting arterial pressure and heart rate were measured on three consecutive days before and after training. MSNA was recorded on the third day.
Effects of isometric handgrip training dose on resting blood pressure and resistance vessel endothelial function in normotensive women
Elizabeth D. Badrov, Brad S. Fleenor, et al.
Dose-dependent effects of IHG training on BP and endothelial function.
Cardiovascular stress reactivity tasks successfully predict the hypotensive response of isometric handgrip training in hypertensives
Elizabeth D. Badrov, David S. Taylor, et al.
Cardiovascular stress reactivity predicts hypotensive response to IHG training.
Cardiovascular benefits of controlled isometric training may be due to improvement in endothelial function via up regulation of nitric oxide synthase through shear stress induced transcriptional mechanisms
Shane A. Phillips, et al.
Mechanisms of cardiovascular benefits via endothelial function and nitric oxide synthase.
Isometric handgrip training improves local flow-mediated dilation in medicated hypertensives
Cheri J. W. et al.
IHG training improves endothelial function in medicated hypertensive patients.
Current Evidence on the Hemodynamic and Blood Pressure Effects of Isometric Exercise in Normotensive and Hypertensive Persons
Steve G. Chrysant
Review of hemodynamic and BP effects of isometric exercise.
Isometric handgrip training does not improve flow-mediated dilation in subjects with normal blood pressure
Matthew J. Smith, et al.
No improvement in endothelial function after IHG training in normotensives.
Impact of Resistance Training on Blood Pressure and Other Cardiovascular Risk Factors: A Meta-Analysis of Randomized, Controlled Trials
Veronique A. Cornelissen, Neil A. Smart
Meta-analysis of resistance and IHG training on BP reduction.
Evaluation of CardioGrip as a Therapeutic Intervention in Hypertension and Vascular Disease
D. Baker, et al.
CardioGrip device assessment in hypertension management.
The effects of isometric exercise training on resting blood pressure and orthostatic tolerance in humans
Linda L. McGowan, et al.
Effects of isometric training on BP and orthostatic tolerance.
Regular Isometric Handgrip Training Lowers and Controls Blood Pressure in Hypertensive Patients; 4 One Year Cases
J. Geisburg
Case reports on BP control with IHG training.
Beyond Medications and Diet: Alternative Approaches to Lowering Blood Pressure : A Scientific Statement From the American Heart Association
Robert D. Brook, et al.
Scientific statement on alternative BP lowering methods including IHG.
Isometric handgrip training improves local flow-mediated dilation in medicated hypertensives
D. J. Jones, et al.
Improvements in BP and endothelial function after IHG training.
Effect of isometric exercise on resting blood pressure: a meta analysis
Jennifer A. Kelley, Kristi S. Kelley
Meta-analysis confirming isometric exercise reduces BP.
Hypotension following mild bouts of resistance exercise and submaximal dynamic exercise
M. J. MacDonald, et al.
Hypotensive responses post mild resistance and dynamic exercise.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
S. A. McGowan, et al.
Isometric training lowers resting BP.
Isometric Training Lowers Resting Blood Pressure and Modulates Autonomic Control
S. L. McGowan, et al.
IHG training modulates autonomic control and reduces BP.
Effects of isometric handgrip training among people medicated for hypertension: a multilevel analysis
Philip J. Millar, et al.
Analysis of IHG effects in medicated hypertensives.
Isometric handgrip training lowers blood pressure and increases heart rate complexity in medicated hypertensive patients
Philip J. Millar, et al.
IHG training reduces BP and increases heart rate variability.
Effect of short-term isometric handgrip training on blood pressure in middle-aged females
Joanna Mortimer, Andrew J. McKune
Short-term IHG effects on BP in middle-aged females.
Scientific Evidence that Isometric Exercise Reduces Blood Pressure
Various (Review article)
Review of studies supporting BP lowering by isometric exercise.
Short-term isometric exercise reduces systolic blood pressure in hypertensive adults: Possible role of reactive oxygen species (R1)
A. A. Whelton, et al.
Mechanisms of SBP reduction via reactive oxygen species.
The Effect of Isometric Arm or Leg Exercise on Resting Blood Pressure and Arterial Distensibility in Persons Medicated For Hypertension
Philip J. Millar, et al.
Effects of isometric arm/leg exercise on BP and arterial health.
MAYO CLINIC HEALTH LETTER Reliable Information for a Healthier Life - Diverticular disease
Mayo Clinic Health Information Team
Health information on diverticular disease (not related to IHG).